CALCIUM BINDING BY CHONDROITIN SULFATE

被引：45

作者：

URIST, MR

SPEER, DP

IBSEN, KJ

STRATES, BS

机构：

[1] Bone Research Laboratory, School of Medicine, University of California, Los Angeles, 90024, California

来源：

CALCIFIED TISSUE RESEARCH | 1968年 / 2卷 / 03期

关键词：

Binding; Calcium; Cartilage; Chondroitin; Ion;

D O I：

10.1007/BF02279213

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The binding of calcium by chondroitin sulfate C was studied by employing biological and physicochemical methods for the quantitative determination of ionic calcium. Mean values for log Kj, the logarithm of the uncorrected formation constant for a calcium-chondroitin sulfate complex, were 1.64 with the frog heart technique, 1.55 with the murexide method, 1.39 with ultrafiltration and 1.04 with the calcium selective electrode. The magnitude of these values suggests that chondroitin sulfate has a relatively high binding capacity for calcium, but calculated values for an exchange parameter Kp indicate that calcium has a low affinity for the polysaccharide. © 1968 Springer-Verlag.

引用

页码：253 / &

共 26 条

[1] CALCIUM BINDING BY CHONDROITIN SULFATE ASSOCIATED WITH COLLAGEN [J].