PLUS AND MINUS SINGLE-STRANDED DNA SEPARATELY ENCAPSIDATED IN ADENO-ASSOCIATED SATELLITE VIRIONS

被引：86

作者：

MAYOR, HD

TORIKAI, K

MELNICK, JL

MANDEL, M

机构：

[1] Baylor College of Medicine, Houston

[2] University of Texas M. D. Anderson Hospital, Tumor Institute at Houston, Houston

来源：

SCIENCE | 1969年 / 166卷 / 3910期

关键词：

D O I：

10.1126/science.166.3910.1280

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Based on physical and chemical determinations, the molecular weight of the type 4 adeno-satellite virus is 5.4×106 daltons, and the virion contains 1.4×106 daltons of DNA. Denaturation and renaturation studies indicate that the viral genome is a single-stranded DNA molecule and that each virion contains either a minus or a plus strand. Upon extraction, the minus and plus strands unite to form double-stranded DNA molecules with no obvious excess of unpaired strands.

引用

页码：1280 / &

共 23 条

[1] DETECTION OF NUCLEAR ANTIGENS (DNA) IN NORMAL AND PATHOLOGIC HUMAN FLUIDS BY QUANTITATIVE COMPLEMENT FIXATION [J].