2,3-DIHYDRO-5-BENZOFURANOLS AS ANTIOXIDANT-BASED INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS

被引：46

作者：

HAMMOND, ML ^{[1
]}

KOPKA, IE ^{[1
]}

ZAMBIAS, RA ^{[1
]}

CALDWELL, CG ^{[1
]}

BOGER, J ^{[1
]}

BAKER, F ^{[1
]}

BACH, T ^{[1
]}

LUELL, S ^{[1
]}

MACINTYRE, DE ^{[1
]}

机构：

[1] MERCK SHARP & DOHME RES LABS,DEPT BIOCHEM & MOLEC PATHOL,RAHWAY,NJ 07065

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1989年 / 32卷 / 05期

关键词：

D O I：

10.1021/jm00125a014

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1006 / 1020

页数：15

共 59 条

[1] INVITRO EFFECTS OF SYNTHETIC ANTIOXIDANTS AND VITAMIN-E ON ARACHIDONIC-ACID METABOLISM AND THROMBOXANE FORMATION IN HUMAN-PLATELETS AND ON PLATELET-AGGREGATION
AGRADI, E
PETRONI, A
SOCINI, A
GALLI, C
[J]. PROSTAGLANDINS, 1981, 22 (02): : 255 - 266
[2] AHARONY D, 1986, J BIOL CHEM, V261, P1512
[3] SYNTHESIS AND 5-LIPOXYGENASE INHIBITORY ACTIVITIES OF EICOSANOID COMPOUNDS
ARAI, Y
SHIMOJI, K
KONNO, M
KONISHI, Y
OKUYAMA, S
IGUCHI, S
HAYASHI, M
MIYAMOTO, T
TODA, M
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1983, 26 (01) : 72 - 78
[4] BIOCHEMICAL AND BIOLOGICAL-ACTIVITIES OF 2,3-DIHYDRO-6-[3-(2-HYDROXYMETHYL)PHENYL-2-PROPENYL]-5-BENZOFURANOL (L-651,896), A NOVEL TOPICAL ANTIINFLAMMATORY AGENT
BONNEY, RJ
DAVIES, P
DOUGHERTY, H
EGAN, RW
GALE, PH
CHANG, M
HAMMOND, M
JENSEN, N
MACDONALD, J
THOMPSON, K
ZAMBIAS, R
OPAS, EE
MEURER, R
PACHOLOK, S
HUMES, JL
[J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (22) : 3885 - 3891
[5] REARRANGEMENT OF ALLYL ARYL ETHERS ALD ALLYL CYCLOHEXADIENONES USING BORON TRICHLORIDE
BORGULYA, J
MADEJA, R
FAHRNI, P
HANSEN, HJ
SCHMID, H
BARNER, R
[J]. HELVETICA CHIMICA ACTA, 1973, 56 (01) : 14 - 75
[6] BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P77
[7] AUTOXIDATION OF BIOLOGICAL MOLECULES .4. MAXIMIZING THE ANTIOXIDANT ACTIVITY OF PHENOLS
BURTON, GW
DOBA, T
GABE, EJ
HUGHES, L
LEE, FL
PRASAD, L
INGOLD, KU
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (24) : 7053 - 7065
[8] LEUKOTRIENE BIOSYNTHESIS INHIBITORS
CASHMAN, JR
[J]. PHARMACEUTICAL RESEARCH, 1985, (06) : 253 - 261
[9] INHIBITION-KINETICS OF CHAIN-BREAKING PHENOLIC ANTIOXIDANTS IN SDS MICELLES - EVIDENCE THAT INTERMICELLAR DIFFUSION RATES MAY BE RATE-LIMITING FOR HYDROPHOBIC INHIBITORS SUCH AS ALPHA-TOCOPHEROL
CASTLE, L
PERKINS, MJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1986, 108 (20) : 6381 - 6382
[10] RATIONALLY DESIGNED, POTENT COMPETITIVE INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS
COREY, EJ
CASHMAN, JR
KANTNER, SS
WRIGHT, SW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (05) : 1503 - 1504

← 1 2 3 4 5 6 →