UNUSUAL REACTION TO CHLORAMBUCIL - A CASE-REPORT

被引：18

作者：

PIETRANTONIO, F

MORICONI, L

TORINO, F

ROMANO, A

GARGOVICH, A

机构：

[1] UNIV CATTOLICA SACRO CUORE, IST CLIN MED, I-00168 ROME, ITALY

[2] UNIV CATTOLICA SACRO CUORE, IST CLIN DERMATOL, I-00168 ROME, ITALY

来源：

CANCER LETTERS | 1990年 / 54卷 / 03期

关键词：

chlorambucil; chronic lymphatic leukemia; toxic epidermal necrolisis;

D O I：

10.1016/0304-3835(90)90030-2

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this brief report we describe, a case of cutaneous reaction during treatment of chronic lymphatic leukemia (CLL) with chlorambucil. The patient developed a confluent maculopapular erythema and large flaccid bullae of trunk, legs, feet and mucous membranes, with fever up to 38°C. Toxic epidermal necrolisis (TEN) was supposed and the diagnosis was confirmed by a skin patch test followed by cutaneous biopsy. TEN by chlorambucil is a rare syndrome that may be considered in presence of cutaneous reaction to this drug. © 1990.

引用

页码：109 / 111

页数：3

共 8 条

[1] THE CULPRIT DRUGS IN 87 CASES OF TOXIC EPIDERMAL NECROLYSIS (LYELLS SYNDROME) [J].