CHLOROQUINE-RESISTANT PLASMODIUM-VIVAX IN PAPUA-NEW-GUINEA

被引：87

作者：

SCHUURKAMP, GJ ^{[1
]}

SPICER, PE ^{[1
]}

KEREU, RK ^{[1
]}

BULUNGOL, PK ^{[1
]}

RIECKMANN, KH ^{[1
]}

机构：

[1] UNIV SYDNEY,ARMY MALARIA RES UNIT,SYDNEY,NSW 2174,AUSTRALIA

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 1992年 / 86卷 / 02期

关键词：

D O I：

10.1016/0035-9203(92)90531-G

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

An Australian expatriate on regular weekly antimalarial prophylaxis with chloroquine base and Maloprim(R) developed symptomatic Plasmodium vivax infection which failed to respond adequately to 600 mg of chloroquine base. More ominously, a resident of the Highlands region of Papua New Guinea contracted vivax malaria which failed to be cleared by 2400 mg chloroquine base administered over 4 d. Both patients had achieved appropriate blood and plasma concentrations of chloroquine after treatment. Chloroquine-resistant P. vivax is now a clinical fact in Papua New Guinea.

引用

页码：121 / 122

页数：2

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