DATURA DELIRIUM

被引：22

作者：

HANNA, JP

SCHMIDLEY, JW

BRASELTON, WE

机构：

[1] CASE WESTERN RESERVE UNIV,SCH MED,DEPT NEUROL,CLEVELAND,OH 44106

[2] CLEVELAND METROPOLITAN GEN HOSP,DEPT NEUROL,CLEVELAND,OH 44109

[3] MICHIGAN STATE UNIV,DEPT PHARMACOL & TOXICOL,E LANSING,MI 48824

来源：

CLINICAL NEUROPHARMACOLOGY | 1992年 / 15卷 / 02期

关键词：

DATURA; TROPINE ALKALOIDS; PHYSOSTIGMINE;

D O I：

10.1097/00002826-199204000-00004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Poisoning with tropine alkaloids from cultivated plants and pharmaceuticals is an uncommon cause of delirium and coma. We report a patient with a toxic delirium following ingestion of the tropine alkaloid-containing root of Datura innoxia. Thin-layer chromatography and gas chromatography/mass spectrometry confirmed the presence of atropine and scopolamine in samples of the ingested root. Routine clinical toxin screens may not include an assay for tropine alkaloids. A specific tropine alkaloid assay may provide supporting evidence. The clinical, electroencephalographic, and therapeutic aspects of anticholinergic poisoning are discussed.

引用

页码：109 / 113

页数：5

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