EFFICIENT ROUTES TO CYCLIC 2,3-EPOXYALCOHOLS FROM CYCLOALKENYL KETONES, VIA CYCLOALKENYL ALCOHOLS

被引：14

作者：

MARSON, CM

WALKER, AJ

PICKERING, J

HARPER, S

WRIGGLESWORTH, R

EDGE, SJ

机构：

[1] SANDOZ INST MED RES,LONDON WC1E 6BN,ENGLAND

[2] HEXCEL CHEM PROD LTD,MIDDLESBROUGH TS2 1UB,CLEVELAND,ENGLAND

来源：

TETRAHEDRON | 1993年 / 49卷 / 45期

关键词：

D O I：

10.1016/S0040-4020(01)80560-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The minimising of torsional strain and non-bonding interactions is proposed as the explanation of high diastereoselectivity observed in the epoxidation of cycloalkenyl alcohols. reported for twenty three examples. The resulting 2,3-epoxyalcohols are key intermediates in the synthesis of tricyclic 1, 2-diols and beta-hydroxy ketones

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页码：10317 / 10338

页数：22

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