INSULIN RESISTANCE AND COMPENSATORY HYPERINSULINEMIA - ROLE IN HYPERTENSION, DYSLIPIDEMIA, AND CORONARY HEART-DISEASE

被引:228
作者
REAVEN, GM [1 ]
机构
[1] STANFORD UNIV,MED CTR,SCH MED,DEPT MED,STANFORD,CA 94305
关键词
D O I
10.1016/0002-8703(91)90434-J
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Resistance to insulin-stimulated glucose uptake and hyperinsulinemia may play a central role in the cause and clinical course of patients with non-insulin-dependent diabetes mellitus, high blood pressure, abnormalities of lipoprotein metabolism, and coronary heart disease. This article summarizes the evidence in support of this general hypothesis.
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页码:1283 / 1288
页数:6
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