INTRAMOLECULAR ATTACK BY THE HYDROXY GROUP ON PHOSPHATE DIESTERS IS BOTH GENERAL ACID AND GENERAL BASE-CATALYZED

被引：23

作者：

CHANDLER, AJ ^{[1
]}

KIRBY, AJ ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,CAMBRIDGE CB2 1EW,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 24期

关键词：

D O I：

10.1039/c39920001769

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Buffers catalysing the hydrolysis of a phosphate diester with a neighbouring nucleophilic OH group act as general acids, general bases, or both, depending on their pK(a), though the rate determining step remains the same.

引用

页码：1769 / 1770

页数：2

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