NEAR-INFRARED FOURIER-TRANSFORM RAMAN-SPECTROSCOPIC STUDY OF HUMAN BRAIN-TISSUES AND TUMORS

被引:115
作者
MIZUNO, A
KITAJIMA, H
KAWAUCHI, K
MURAISHI, S
OZAKI, Y
机构
[1] JIKEI UNIV SCH MED,DEPT NEUROSURG,MINATO KU,TOKYO 105,JAPAN
[2] JEOL CO LTD,DIV ANALYT INSTRUMENTS,AKISHIMA 196,JAPAN
[3] KWANSEI GAKUIN UNIV,SCH SCI,DEPT CHEM,NISHINOMIYA,HYOGO 662,JAPAN
关键词
D O I
10.1002/jrs.1250250105
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
Non-destructive examination of human brain tissues and several kinds of brain tumours using near-infrared (1064 nm) excited Fourier transform (NIR-FT) Raman spectroscopy is reported. The spectra from normal but oedematous grey and white matter were similar to those of normal rat grey and white matter reported previously. The brain tumours investigated (glioma grade II and III, two acoustic neurinomas and central neurocytoma) gave Raman spectra essentially the same as to that of grey matter. Histological examination of glioma grade III revealed extracellular PAS-positive materials, which have a band at 8-56 cm-1 due to polysaccharides. One of the neurinoma contained a carotenoid which exhibited two resonance Raman peaks at 1157 and 1524 cm-1; another neurinoma did not contain the carotenoid. The appearance of a strong Raman peak at 960 cm-1 suggested that the central neurocytoma of choroid plexus was calcified.
引用
收藏
页码:25 / 29
页数:5
相关论文
共 16 条
[1]  
CAREY PR, 1982, BIOCH APPLICATIONS R
[2]  
KITAJIMA T, 1992, TOKYO JIKEIKAI MED J, V107, P935
[3]  
KLAZO I, 1967, J NEUROPATHOL EXP NE, V26, P1
[5]  
MANTELE W, 1991, BIOCHIM BIOPHYS ACTA, V1057, P3678
[6]  
MATHEWSROTH MM, 1977, NUTR REP INT, V16, P419
[7]   NEAR-INFRARED FT-RAMAN SPECTRA OF THE RAT-BRAIN TISSUES [J].
MIZUNO, A ;
HAYASHI, T ;
TASHIBU, K ;
MARAISHI, S ;
KAWAUCHI, K ;
OZAKI, Y .
NEUROSCIENCE LETTERS, 1992, 141 (01) :47-52
[8]   NONDESTRUCTIVE STRUCTURAL-ANALYSIS OF PHOTOSYNTHETIC PIGMENTS IN LIVING RHODOBACTER-SPHAEROIDES MUTANTS BY NEAR-INFRARED FOURIER-TRANSFORM RAMAN-SPECTROSCOPY [J].
OKADA, K ;
NISHIZAWA, E ;
FUJIMOTO, Y ;
KOYAMA, Y ;
MURAISHI, S ;
OZAKI, Y .
APPLIED SPECTROSCOPY, 1992, 46 (03) :518-523
[9]   MEDICAL APPLICATION OF RAMAN-SPECTROSCOPY [J].
OZAKI, Y .
APPLIED SPECTROSCOPY REVIEWS, 1988, 24 (3-4) :259-312
[10]  
OZAKI Y, 1992, APPL SPECTROSC, V46, P335