CARDIAC T-TYPE CALCIUM CURRENT - PHARMACOLOGY AND ROLES IN CARDIAC TISSUES

被引:79
作者
VASSORT, G [1 ]
ALVAREZ, J [1 ]
机构
[1] INST CARDIOL & CIRUGIA CARDIOVASC, ELECTROFISIOL LAB, HAVANA, CUBA
关键词
HEART; CALCIUM; IONIC CHANNEL; AUTONOMIC NERVOUS SYSTEM; ARRHYTHMIA;
D O I
10.1111/j.1540-8167.1994.tb01175.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Modulation of T-Type Calcium Channels. A low threshold, voltage-gated calcium current is reported in most cardiac tissues but rarely in ventricular cells. This article reports some recently described characteristics and discusses their possible pathophysiologic implications. It also reviews the alterations induced in this current by a variety of chemical agents including several neuromediators in cardiac and other tissues.
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页码:376 / 393
页数:18
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