VALPROATE IN STATUS EPILEPTICUS

被引：16

作者：

HOLLE, LM

GIDAL, BE

COLLINS, DM

机构：

[1] UNIV WISCONSIN, SCH PHARM, DEPT NEUROL, MADISON, WI 53706 USA

[2] UNIV WISCONSIN HOSP & CLIN, SCH PHARM, DEPT NEUROL, MADISON, WI 53792 USA

来源：

ANNALS OF PHARMACOTHERAPY | 1995年 / 29卷 / 10期

关键词：

D O I：

10.1177/106002809502901017

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In patients with intractable status epilepticus who have not responded to therapy with benzodiazepines, phenytoin, and barbiturates, valproate may be a reasonable option. Extemporaneously prepared valproate rectal suppositories or retention enemas have been given in dosages of 200-1200 mg q6h in addition to phenytoin, phenobarbital, or both in adults. The pediatric dose used was 15-20 mg/kg, in addition to phenytoin and/or phenobarbital.

引用

页码：1042 / 1044

页数：3

共 15 条

[1] EFFECTS OF VALPROATE IN A MODEL NERVOUS-SYSTEM (BUCCAL GANGLIA OF HELIX-POMATIA) .1. ANTIEPILEPTIC ACTIONS [J].