PROTEINASE-INHIBITORS OF BOVINE NASAL CARTILAGE

被引：90

作者：

ROUGHLEY, PJ

MURPHY, G

BARRETT, AJ

机构：

来源：

BIOCHEMICAL JOURNAL | 1978年 / 169卷 / 03期

关键词：

D O I：

10.1042/bj1690721

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Extracts from bovine nasal cartilage with 1M-guanidinium chloride were fractionated by ultrafiltration. Gel chromatography of the low molecular weight material resolved three distinct fractions with inhibitory activity against (a) collagenases (22000 mol.wt.), (b) thiol proteinases cathepsin B and papain (13 000 mol.wt.), and (c) trypsin and other serine proteinases (7000 mol.wt.).

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页码：721 / 724

页数：4

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