A NOVEL INVITRO CHEMOSENSITIVITY TEST USING MATERIALS COLLECTED BY ENDOSCOPIC BIOPSY

被引：10

作者：

HIRAI, T

KAWANO, K

HIRABAYASHI, N

NISHIYAMA, M

YAMASHITA, Y

MUKAIDA, H

IWATA, T

TOGE, T

机构：

[1] Department of Surgery, Hiroshima University

来源：

ANTI-CANCER DRUGS | 1991年 / 2卷 / 03期

关键词：

ATP ASSAY; BIOPSY; CHEMOSENSITIVITY TEST; ENDOSCOPE; ESOPHAGEAL CANCER;

D O I：

10.1097/00001813-199106000-00008

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The usefulness of chemosensitivity testing of cells collected by endoscopic biopsy using the adenosine triphosphate assay (ATP assay) was investigated for esophageal tumors. Correlation between this chemosensitivity test and other chemosensitivity tests was more than 80% in most combinations. The predictive rate of clinical sensitivity was 77.8% and of clinical resistance was 68.8%. The predictive accuracy was 72.0%. These results will extend the indication and usefulness of chemosensitivity testing in inoperable and preoperable cases.

引用

页码：269 / 274

页数：6

共 12 条

[1]

BOGDEN AE, 1984, CANCER RES, V44, P1087

[2]

FUKUI H, 1987, JPN J CANCER CHEMOTH, V14, P1106

[3]

GRIFFIN TW, 1983, CANCER, V52, P2185, DOI 10.1002/1097-0142(19831215)52:12<2185::AID-CNCR2820521202>3.0.CO

[4]

2-P

[5] COMPARATIVE-STUDIES ON INVITRO HUMAN TUMOR CLONOGENIC-ASSAY (HTCA) AND INVIVO NUDE MOUSE-ISOTOPE ASSAY (NM-IA) [J].

HIRABAYASHI, N ;

NOSO, Y ;

NIIMI, K ;

NISHIYAMA, M ;

YAMAGUCHI, M ;

TOGE, T ;

NIIMOTO, M ;

HATTORI, T .

JAPANESE JOURNAL OF SURGERY, 1987, 17 (02) :104-109

[6] BYPASS OPERATION FOR ADVANCED ESOPHAGEAL CANCER - AN ANALYSIS OF 93 CASES [J].

HIRAI, T ;

YAMASHITA, Y ;

MUKAIDA, H ;

KAWANO, K ;

TOGE, T ;

NIIMOTO, M ;

HATTORI, T .

JAPANESE JOURNAL OF SURGERY, 1989, 19 (02) :182-188

[7] A SIMPLE AND RAPID INVITRO TEST FOR DETERMINING SENSITIVITY OF CANCER-CELLS TO ANTICANCER DRUGS [J].

ICHIHASHI, H ;

NOGAKI, M ;

YAMAUCHI, M ;

TAKAGI, H ;

KONDO, T ;

OZAWA, T .

JAPANESE JOURNAL OF SURGERY, 1986, 16 (05) :380-383

[8]

KANGAS L, 1984, MED BIOL, V62, P338

[9]

KUZMITS R, 1984, ADV EXP MED BIOL, V165, P383

[10]

MAEHARA Y, 1986, JPN J CANC CHEMOTHER, V13, P2342

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