STEREODIVERGENT SYNTHESIS OF FLUORINATED THREONINE DERIVATIVES IN HIGH OPTICAL PURITY

被引：22

作者：

SHIMIZU, M ^{[1
]}

YOKOTA, T ^{[1
]}

FUJIMORI, K ^{[1
]}

FUJISAWA, T ^{[1
]}

机构：

[1] MIE UNIV,DEPT CHEM MAT,TSU,MIE 514,JAPAN

来源：

TETRAHEDRON-ASYMMETRY | 1993年 / 4卷 / 05期

关键词：

D O I：

10.1016/S0957-4166(00)80121-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Fluorinated 3-acetoxy-2-(methoxyimino)butyrates were resolved by lipase to give the corresponding alcohols and the acetates in high optical purity. The resolved alcohols were readily converted into mono-, di-, and trifluorothreonine and allo-threonine derivatives by hydrogenation of the methoxyimino group.

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页码：835 / 838

页数：4

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