ELECTROPHILIC SUBSITUTION IN 2,1-BENZISOTHIAZOLES

被引：16

作者：

DAVIS, M

WHITE, AW

机构：

[1] Department of Chemistry, La Trobe University, Bundoora

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 16期

关键词：

D O I：

10.1039/j39690002189

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bromination of 2,1-benzisothiazole (I) under conditions in which Br + is the electrophilic species gives a mixture of 5- and 7-bromo-2,1-benzisothiazole, together with a smaller quantity of 4,7-dibromo-2,1-benzisothiazole. Nitration of 2,1-benzisothiazole affords mainly 5-nitro-2,1-benzisothiazole with smaller quantities of the 7-nitro-and 4-nitro-isomers. Nitration of monosubstituted 2,1-benzisothiazoles gives products which indicate that the substituent group already present in the benzenoid ring is the decisive directing influence.

引用

页码：2189 / &

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