HLA SERUM SCREENING BASED ON AN HEURISTIC SOLUTION OF THE SET COVER PROBLEM

被引:6
作者
WOODBURY, MA
CIFTAN, EA
AMOS, DB
机构
[1] Duke University Medical Center, Durham
来源
COMPUTER PROGRAMS IN BIOMEDICINE | 1979年 / 9卷 / 03期
关键词
FORTRAN; NP-complete; Serology; Serum screening; Specificities;
D O I
10.1016/0010-468X(79)90038-2
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
A computer program initially written by the Milwaukee Blood Bank has been modified to use a new algorithm for the assignment of HLA specificities to antisera. The assignment is based on the reactions of cells with known specificities. Specificities which are present only on cells which do not react are first ruled out. This step is followed by one or more steps in which the 'least reactive' specificities are ruled out. The rationale for the algorithm is discussed and an example is presented. © 1979.
引用
收藏
页码:263 / 273
页数:11
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