DIRECTED ORTHO-METALATION STUDIES ON PODOCARPIC ACID-DERIVATIVES - ADVANTAGEOUS USE OF A LICKOR BASE

被引：7

作者：

CAMBIE, RC ^{[1
]}

HIGGS, PI ^{[1
]}

LEE, KC ^{[1
]}

METZLER, MR ^{[1
]}

RUTLEDGE, PS ^{[1
]}

STEVENSON, RJ ^{[1
]}

WOODGATE, PD ^{[1
]}

机构：

[1] UNIV AUCKLAND,DEPT CHEM,AUCKLAND,NEW ZEALAND

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1991年 / 44卷 / 10期

关键词：

D O I：

10.1071/CH9911465

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Methyl 13-(N,N-diethylcarbamoyl)-12-methoxypodocarpa-8,11,13-trien-19-oate (2), 13-(N,N-diethylcarbamoyl)-12, 19-dimethoxypodocarpa-8,11,13-triene (8) and N,N-diethyl-2-methoxy-4, 5-dimethylbenzamide (15) were prepared for studies involving lithiation directed ortho to the tertiary amide group, in which the use of a LICKOR base was advantageous. Some dynamic features of the n.m.r. spectra of the amides are discussed. Oxazoline derivatives of both the monocyclic and diterpenoid compounds were synthesized.

引用

页码：1465 / 1477

页数：13

共 34 条

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