THE REGULATION AND FUNCTION OF P21(RAS) DURING T-CELL ACTIVATION AND GROWTH

被引:137
作者
PASTOR, MI [1 ]
REIF, K [1 ]
CANTRELL, D [1 ]
机构
[1] IMPERIAL CANC RES FUND,LYMPHOCYTE ACTIVAT LAB,LONDON WC2A 3PX,ENGLAND
来源
IMMUNOLOGY TODAY | 1995年 / 16卷 / 03期
关键词
D O I
10.1016/0167-5699(95)80134-0
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The delivery of signals that control the growth of T cells is a key event for effective co-ordination of T-cell-dependent immune responses. It is now recognized that guanine nucleotide binding proteins play an important role in signal transduction by the T-cell receptor (TCR) and cytokine receptors. Here, Manolo Izquierdo Pastor, Karin Reif and Doreen Cantrell review the numerous recent advances in understanding how the p21(ras) guanine nucleotide binding protein couples the TCR to the T-cell signalling cascade.
引用
收藏
页码:159 / 164
页数:6
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