OXA-14, ANOTHER EXTENDED-SPECTRUM VARIANT OF OXA-10 (PSE-2) BETA-LACTAMASE FROM PSEUDOMONAS-AERUGINOSA

被引：92

作者：

DANEL, F ^{[1
]}

HALL, LMC ^{[1
]}

GUR, D ^{[1
]}

LIVERMORE, DM ^{[1
]}

机构：

[1] UNIV HACETTEPE,SCH MED,DEPT INTERNAL MED,INFECT DIS SECT,ANKARA 06100,TURKEY

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 08期

关键词：

D O I：

10.1128/AAC.39.8.1881

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Pseudomonas aeruginosa 455, isolated in Ankara, Turkey, produced a pI 6.2 beta-lactamase determined by plasmid pMLH53 and resisted all beta-lactams except carbapenems. This beta-lactamase, named OXA-14, corresponded to OXA-10 (PSE-2) except that aspartate replaced glycine at position 157 and thus is intermediate between OXA-10 and OXA-11, which has aspartate at position 157 and a further substitution at position 143.

引用

页码：1881 / 1884

页数：4

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