NEUROPEPTIDE PARTICIPATION IN CANINE LARYNGEAL SENSORY INNERVATION - IMMUNOHISTOCHEMISTRY AND RETROGRADE LABELING

被引：21

作者：

HISA, Y ^{[1
]}

OKAMURA, H ^{[1
]}

TADAKI, N ^{[1
]}

TAGUCHI, JI ^{[1
]}

UNO, T ^{[1
]}

IBATA, Y ^{[1
]}

机构：

[1] KYOTO PREFECTURAL UNIV MED, DEPT ANAT, KYOTO 602, JAPAN

来源：

ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY | 1994年 / 103卷 / 10期

关键词：

AFFERENT SYSTEM; CALCITONIN GENE-RELATED PEPTIDE; CANINE; CHOLERA TOXIN; ENKEPHALIN; LARYNGEAL NERVE; NODOSE GANGLION; SUBSTANCE P;

D O I：

10.1177/000348949410301004

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

We investigated the quantitative participation of calcitonin gene-related peptide (CGRP), substance P (SP), and leu-enkephalin (ENK) in canine laryngeal sensory innervation by immunohistochemistry in combination with retrograde labeling using the recently introduced retrograde tracer cholera toxin subunit B-conjugated gold (CTBG). In the nodose ganglion, neurons labeled from the internal branch of the superior laryngeal nerve with CTBG were investigated immunohistochemically by means of antisera against CORP, SP, and ENK. The percentages of neurons immunoreactive to each neuropeptide were as follows: CGRP 81.5%, SP 24.5%, and ENK 7.0%. These results suggest that CGRP is the main sensory neurotransmitter in canine laryngeal sensory innervation.

引用

页码：767 / 770

页数：4

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