Three-dimensional triple quantum-filtered Na-23 imaging of rabbit kidney with weighted signal averaging

被引：23

作者：

Bansal, N

Seshan, V

机构：

[1] Department of Radiology, The Mary Nell and Ralph B. Rogers Magnetic Resonance Center, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, 75235‐9085

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1995年 / 5卷 / 06期

关键词：

Na-23; MRI; multiple quantum NMR; kidney;

D O I：

10.1002/jmri.1880050624

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Low signal-to-noise ratio (SNR) has been the main obstacle to multiple quantum-filtered Na-23 imaging becoming an important technique for biologic and clinical applications. Through computer simulations and phantom experiments, we show that the SMI in Na-23 imaging can be substantially improved by weighted signal averaging, Three-dimensional single quantum and triple quantum (Tg)-filtered Na-23 images of an externalized rabbit kidney were collected with this technique, The TQ-filtered image did not show any signal when the animal was alive. However, upon sacrificing the animal, the renal cortex became clearly visible without any significant increase in signal from the medullary region, This increase in TQ-filtered signal in the renal cortex may be caused by an increased concentration of intracellular Na+ in the large intracellular space present herein, compared with the medulla, To our knowledge, this study represents the first example of three-dimensional TQ-filtered Na-23 image of a biological sample.

引用

页码：761 / 767

页数：7

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