VARIABLES PREDICTIVE OF SURVIVAL IN PATIENTS WITH CORONARY-DISEASE - SELECTION BY UNIVARIATE AND MULTIVARIATE ANALYSES FROM THE CLINICAL, ELECTROCARDIOGRAPHIC, EXERCISE, ARTERIOGRAPHIC, AND QUANTITATIVE ANGIOGRAPHIC EVALUATIONS

被引:627
作者
HAMMERMEISTER, KE
DEROUEN, TA
DODGE, HT
机构
[1] VET ADM HOSP,CARDIOVASC DIS SERV,SEATTLE,WA 98108
[2] UNIV WASHINGTON,DEPT BIOSTAT,SEATTLE,WA 98195
[3] UNIV WASHINGTON,DIV CARDIOL,SEATTLE,WA 98195
关键词
D O I
10.1161/01.CIR.59.3.421
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A progression of univariate followed by multivariate analyses was applied to 46 variables selected from the clinical examination, exercise test, coronary arteriography, and quantitative angiographic assessment of left ventricular function in patients with coronary disease to determine those variables most predictive of survival. For the 733 medically treated patients, the final Cox's regression analysis showed that the left ventricular ejection fraction was most predictive of survival, followed by age, number of vessels with stenosis(es) ≥70%, and ventricular arrhythmia on the resting electrocardiogram. For the 1870 surgically treated patients, ventricular arrhythmia on the resting electrocardiogram was most predictive of survival followed by ejection fraction, heart murmur, left main coronary artery stenosis ≥50%, and use of diuretic agents.
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页码:421 / 430
页数:10
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