FOCAL EPILEPTOGENESIS AFTER INTRA-CORTICAL HEMOGLOBIN INJECTION

被引：80

作者：

ROSEN, AD

FRUMIN, NV

机构：

[1] Department of Neurology, State University of New York, Stony Brook

来源：

EXPERIMENTAL NEUROLOGY | 1979年 / 66卷 / 02期

关键词：

EEG-electroencephalogram;

D O I：

10.1016/0014-4886(79)90080-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Intracortical injection of purified bovine hemoglobin produced chronic focal spike activity in 89% of rats tested; 50% of the animals evidenced spike activity within 48 h. The lesions produced were pathologically similar to those seen in post-traumatic epilepsy. Evidence is presented suggesting that the neural effect of iron released from hemoglobin may be causally related to the development of a trauma-induced epileptiform focus in humans. © 1979.

引用

页码：277 / 284

页数：8

共 24 条

[1]

[Anonymous], [No title captured]

[2] FACILITATORY AND INHIBITORY EFFECTS OF ELECTROCHEMICAL STIMULATION OF AMYGDALA ON RELEASE OF LUTEINIZING-HORMONE [J].