NICOTINE AND COTININE IN BREAST FLUID

被引：24

作者：

HILL, P

WYNDER, EL

机构：

[1] Naylor Dana Institute for Disease Prevention, American Health Foundation, Valhalla

来源：

CANCER LETTERS | 1979年 / 6卷 / 4-5期

关键词：

D O I：

10.1016/S0304-3835(79)80042-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Breast fluid which bathes the mammary ductal epithelium may contain tumorogenic components. In view of the number of tobacco components inhaled during smoking, it was of interest whether nicotine and its metabolites were present in this fluid. Fluid was obtained from the nipple from menstruating women who were smokers and non-smokers. In smokers, nicotine and cotinine were detectable in the fluid 30 min after smoking. Further analysis of breast fluid may give leads as to whether components present are related to breast carcinogenesis. © 1979 Elsevier/North-Holland Scientific Publishers Ltd., All rights reserved.

引用

页码：251 / 254

页数：4

共 9 条

[1]

HILL P, 1976, MODIFYING RISK SMOKE, V1, P313

[2]

KNOWLES JA, 1969, PEDIATR PHARMACOL TH, V66, P1068

[3]

LONGONE JJ, 1975, RES COMMUN CHEM PATH, V10, P21

[4]

LONGONE JJ, 1973, BIOCHEMISTRY-US, V12, P5025

[5] NICOTINE IN BREAST FLUID OF NON-LACTATING WOMEN [J].

PETRAKIS, NL ;

GRUENKE, LD ;

BEELEN, TC ;

CASTAGNOLI, N ;

CRAIG, JC .

SCIENCE, 1978, 199 (4326) :303-305

[6]

PETRAKIS NL, 1975, J NATL CANCER I, V54, P829

[7]

SARATORIUS O, 1973, J AM MED ASS, V224, P823

[8]

VANVUNAKIS H, 1972, AM J OBSTET GYNECOL, V120, P64

[9]

WYNDER EL, 1977, LANCET, V2, P840

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