THE CYTOMEGALOVIRUS ENHANCER - A PAN-ACTIVE CONTROL ELEMENT IN TRANSGENIC MICE

被引：187

作者：

SCHMIDT, EV ^{[1
]}

CHRISTOPH, G ^{[1
]}

ZELLER, R ^{[1
]}

LEDER, P ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,HOWARD HUGHES MED INST,DEPT GENET,25 SHATTUCK ST,BOSTON,MA 02115

来源：

MOLECULAR AND CELLULAR BIOLOGY | 1990年 / 10卷 / 08期

关键词：

D O I：

10.1128/MCB.10.8.4406

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In an effort to identify widely active regulatory elements, we have examined the action of the cytomegalovirus enhancer-promoter in transgenic mice. These elements activated expression in 24 of 28 tissues tested. The greatest expression was observed in the heart, kidney, brain, and testis. Maximum expression further localized to specific cells within the heart and kidney.

引用

页码：4406 / 4411

页数：6

共 18 条

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