PRIMARY LOCALIZED AMYLOIDOSIS OF THE BLADDER - A CASE OF AL (LAMBDA) AMYLOID PROTEIN AND COMBINATION THERAPY USING DIMETHYL-SULFOXIDE AND CEPHARANTHIN

被引：18

作者：

NISHIYAMA, T

GEJYO, F

KATAYAMA, Y

TAKEDA, M

SATO, S

机构：

[1] Department of Urology, Niigata University School of Medicine

[2] Department of Medicine (II), Niigata University School of Medicine

[3] Department of Urology, Nagaoka Koseiren Central General Hospital

来源：

UROLOGIA INTERNATIONALIS | 1992年 / 48卷 / 02期

关键词：

VESICAL AMYLOIDOSIS; AL (LAMBDA) AMYLOID PROTEIN; COMBINATION THERAPY; DIMETHYL SULFOXIDE; CEPHARANTHIN;

D O I：

10.1159/000282340

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of primary localized amyloidosis of the bladder with amyloid deposits which was characterized as being of immunoglobulin light chain origin (AL) including lambda-type (A lambda) and P component (AP) using the KMnO4 pretreatment method and immunohistochemical procedures. The patient was treated successfully with intravesical dimethyl sulfoxide instillation and oral administration of high-dose cepharanthin after transurethral resection. Combination therapy with dimethyl sulfoxide and cepharanthin was shown to be useful for primary localized amyloidosis of the bladder.

引用

页码：228 / 231

页数：4

共 17 条

[1]

Caldamone A.A., Elbadawi A., Moshtagi A., Frank I.N., Primary localized amyloidosis of urinary bladder, Urology, 15, (1980)

[2]

Fujihara S., Glenner G.G., Primary localized amyloidosis of the genitourinary tract Immunohistochemical study on eleven cases, Lab. Invest., 44, (1981)

[3]

Tokunaka S., Osanai H., Morikawa M., Yachiku S., Experience with dimethyl sulfoxide treatment for primary localized amyloidosis of the bladder, J. Urol., 135, (1986)

[4]

Wright J.R., Calkins E., Humphrey R.L., Potassium permanganate reaction in amyloidosis, A histologic method to assist in differentiating forms of this disease. Lab. Invest., 36, (1977)

[5]

Akhtar M., Valencia M., Thomas A.M., Solitary primary amyloidosis of urinary bladder, Urology, 12, (1978)

[6]

Abramovici I., Chwatt S., Nussenson M., Massive hematuria and perforation in a case of amyloidosis of the bladder: Case report and review of the literature, J. Urol., 118, (1977)

[7]

Shirahara I., Skinner M., Cohen A.S., Gejyo F., Arakawa M., Suzuki M., Hirasawa Y., Histochemical and immunohistochemical characterization of amyloid associated with chronic hemodialysis as β<sub>2</sub>-microglobulin, Lab Invest., 53, pp. 705-709, (1985)

[8]

Gejyo F., Odani S., Yamada T., Homma N., Saito H., Suzuki Y., Nakagawa Y., Kobayashi H., Maruyama Y., Hirasawa Y., Suzuki M., Arakawa M., β<sub>2</sub>-Microglobulin: A new form of amyloid protein associated with chronic hemodialysis, Kidney int., 30, (1986)

[9]

Westermark P., Shirahama T.V., Skinner M., Noren P., Cohen A.S., Amyloid P-component (protein AP) in localized amyloidosis as revealed by an immunocytochcmical method, Histochemist, 71, (1981)

[10]

Windbolz M., Budavari S., Blumetti R.F., Otterbein E.S., The Merck Index, (1983)

← 1 2 →