The gel test, as developed by Lapierre, is an innovative approach to blood group serology. This technology addresses the issue of standardization and incorporates sensitivity, specificity, and efficiency; it is accessible to laboratories of all sizes and levels of expertise. By employing gels premixed with reagents, specific volumes, and a no-wash antiglobulin test that eliminates resuspension of red cell buttons, the gel test reduces the variation inherent in conventional techniques. Applicable to a broad range of tests routinely performed in the blood bank, such as antibody screening, antigen typing, and crossmatching, gel test procedures are easy to perform and yield clear-cut end points that are stable, Plus they can be reviewed at a later time. Applications for the technology reach beyond the routine and potentially into other areas of diagnostic testing.