IS PNEUMONIA REALLY THE OLD MANS FRIEND - 2-YEAR PROGNOSIS AFTER COMMUNITY-ACQUIRED PNEUMONIA

被引:113
作者
BRANCATI, FL
CHOW, JW
WAGENER, MM
VACARELLO, SJ
YU, VL
机构
[1] JOHNS HOPKINS MED INST,WELCH CTR PREVENT EPIDEMIOL & CLIN RES,BALTIMORE,MD 21205
[2] WAYNE STATE UNIV,SCH MED,DIV INFECT DIS,DETROIT,MI 48201
[3] UNIV PITTSBURGH,SCH MED,DIV INFECT DIS,PITTSBURGH,PA 15261
关键词
D O I
10.1016/0140-6736(93)91887-R
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Is pneumonia ''the old man's friend''-a terminal event for patients who will otherwise die soon of underlying chronic disease? If so, chronological age might influence treatment policy. We investigated the predictors of 2-year mortality after patients' admission to hospital for community-acquired pneumonia, and focused on the predictive value of age. In a prospective cohort study 141 consecutive patients were admitted to hospital with community-acquired pneumonia. Clinical, laboratory, and sociodemographic data were collected on admission. Comorbidity was categorised as mild, moderate, or severe by a physician based on the patient's medical history. Survival was assessed at 24 months after discharge. 22 (16%) patients died in hospital. Of the remaining 119, 38 (32%) died over the next 24 months. In a Cox model, 2-year mortality was independently related to severe comorbidity (relative risk [RR] = 9.4) or moderate comorbidity (RR = 3.1), and to haematocrit less than 35% (RR = 2.9) (all p less-than-or-equal-to 0.005). However, compared with patients aged 18-44 years, patients aged 45-64 (RR = 0.84), 65-74 (RR = 1.28), and 75-92 (RR = 1.99) were not significantly more likely to die during the 24 months after discharge (all p greater-than-or-equal-to 0.2). Old age should not be a sole criterion for withholding aggressive treatment of community-acquired pneumonia.
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页码:30 / 33
页数:4
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