SYNTHESIS OF A NEW-GENERATION REVERSE-TRANSCRIPTASE INHIBITOR VIA THE BCL3/GACL3-INDUCED CONDENSATION OF ANILINES WITH NITRILES (SUGASAWA REACTION)

被引：24

作者：

HOUPIS, IN

MOLINA, A

DOUGLAS, AW

XAVIER, L

LYNCH, J

VOLANTE, RP

REIDER, PJ

机构：

[1] Merck Research Laboratories, Process Research, Rahway, NJ 07065, P.O. Box 2000

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 37期

关键词：

D O I：

10.1016/0040-4039(94)85011-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 1 was achieved in high overall yield through a mechanism-based improvement of the preparation of o-acyl anilines.

引用

页码：6811 / 6814

页数：4

共 18 条

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