CHARACTERIZATION OF ANTIBODY TO C-CARBOHYDRATE PRODUCED BY A TRANSPLANTABLE MOUSE PLASMACYTOMA

被引：122

作者：

COHN, M

NOTANI, G

RICE, SA

机构：

[1] The Salk Institute for Biological Studies, La Jolla, CA

来源：

IMMUNOCHEMISTRY | 1969年 / 6卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0019-2791(69)90183-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A transplantable BALB/c mouse plasmacytoma, S63, produces an immunoglobulin with antibody activity directed specifically against the C-carbohydrate of the pneumococcus. This immunoglobylin is of the IgA class and possesses a kappa light chain. The combining site resides in the Fab not the Fc fragment. Some of the antibodies of BALB/c mice induced by C-carbohydrate have the idiotypic determinants which characterize S63-immunoglobulin. © 1969.

引用

页码：111 / &

共 51 条

[1] CARBOXY-TERMINAL AMINO ACIDS OF GAMMA A AND GAMMA M HEAVY CHAINS [J].