METABOLISM OF ATRAZINE BY THE SOLUBLE FRACTION (105000G) FROM CHICKEN LIVER HOMOGENATES

被引:14
作者
FOSTER, TS [1 ]
KHAN, SU [1 ]
AKHTAR, MH [1 ]
机构
[1] AGR CANADA,CHEM & BIOL RES INST,OTTAWA K1A 0C6,ONTARIO,CANADA
关键词
D O I
10.1021/jf60222a003
中图分类号
S [农业科学];
学科分类号
09 ;
摘要
The soluble fraction (105000g) from chicken liver homogenates contains a heat-labile, glutathionedependent enzyme(s) which metabolizes atrazine in in vitro incubations. This is accomplished by conjugation with glutathione and subsequent hydrolysis and partial N-dealkylation to the hydroxy and dealkylated analogues. Evidence is also presented for some dechlorination of the chloro-s-triazine to hydroxy-s-triazine. However, enzymatic hydrolysis of atrazine is the predominant reaction in the soluble fraction from chicken liver homogenates. © 1979, American Chemical Society. All rights reserved.
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页码:300 / 302
页数:3
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