BRASILANE-TYPE SESQUITERPENOIDS FROM THE MEDITERRANEAN RED ALGA LAURENCIA-OBTUSA

被引：15

作者：

AMICO, V ^{[1
]}

CACCAMESE, S ^{[1
]}

NERI, P ^{[1
]}

RUSSO, G ^{[1
]}

FOTI, M ^{[1
]}

机构：

[1] CNR,IST STUDIO SOSTANZE NAT INTERESSE ALIMENTARE & CHIM FARMACEUT,I-95125 CATANIA,ITALY

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 06期

关键词：

LAURENCIA-OBTUSA; RHODOPHYCEAE; RED ALGA; SESQUITERPENES; EPI-BRASILENOL;

D O I：

10.1016/0031-9422(91)85041-W

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new irregular sesquiterpenoids were isolated and characterized, along with epi-brasilenol, from the Mediterranean red alga Laurencia obtusa. They possess the unusual skeleton of brasilane and one of them contains the unprecedented 5,6-double bond (instead of a 1,6-double bond). Their structures were determined by detailed spectral analysis. The relative configurations were assigned by NOESY spectroscopy, molecular mechanics calculations (MM2) and, in one case, by a quantitative computer simulation of the lanthanide induced shifts in the H-1 NMR spectrum.

引用

页码：1921 / 1927

页数：7

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