DEVELOPMENT OF POSTTRAUMATIC CYSTS IN THE SPINAL-CORD OF RATS SUBJECTED TO SEVERE SPINAL-CORD CONTUSION

被引：66

作者：

GUIZARSAHAGUN, G

GRIJALVA, I

MADRAZO, I

FRANCOBOURLAND, R

SALGADO, H

IBARRA, A

OLIVA, E

ZEPEDA, A

机构：

[1] PROYECTO CAMINA AC,CTR INVEST,TLALPAN 4430,MEXICO CITY 14050,MEXICO

[2] INST MEXICANO SEGURO SOCIAL,CTR MED NACL SIGLO 21,HOSP ESPECIALIDADES,DEPT CLIN RES NEUROL DIS,MEXICO CITY 7,DF,MEXICO

[3] NATL AUTONOMOUS UNIV MEXICO,FAC MED,DEPT HISTOL,MEXICO CITY 04510,DF,MEXICO

[4] INST NACL NUTR SALVADOR ZUBIRAN,DEPT BIOCHEM,MEXICO CITY 14000,DF,MEXICO

来源：

SURGICAL NEUROLOGY | 1994年 / 41卷 / 03期

关键词：

EXPERIMENTAL SPINAL CORD INJURY; PARAPLEGIA; POSTTRAUMATIC CYSTS; SPINAL CORD CONTUSION;

D O I：

10.1016/0090-3019(94)90131-7

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

To study the development of post-traumatic spinal cord (SC) cysts, and their fine anatomic characteristics, rats were subjected to severe SC contusion. Specimens were analyzed from day 1 to 1 year post-injury. Using conventional light, and transmission and scanning electron microscopy, three stages were typified, namely: necrosis, repair, and stability. The final cell composition and thickness of the cyst walls were not uniform. Astrocytes, fibroblasts, ependymal cells, and collagen fibers were the main constituents. Chronic inflammatory cells were also observed. The neuropathologic characterization of post-traumatic SC cysts could be useful in planning strategies for SC reconstruction at different times post-injury.

引用

页码：241 / 249

页数：9

共 20 条

[1]

Allen AR, 1911, J AM MED ASS, VLVII, P878, DOI DOI 10.1001/JAMA.1911.04260090100008

[2]

BALENTINE JD, 1978, LAB INVEST, V39, P236

[3]

Barnett HJ, 1976, HDB CLIN NEUROLOGY, P113

[4]

Barnett HJM, 1973, SYRINGOMYELIA MAJOR, VI