POSSIBLE LACK OF FULL CROSS-RESISTANCE OF 5HT(3) ANTAGONISTS - A PILOT-STUDY

被引:3
作者
DEBOER, M
DEWIT, R
STOTER, G
VERWEIJ, J
机构
[1] Department of Medical Oncology, Rotterdam Cancer Institute/Dr. Daniel den Hoed Kliniek, Rotterdam, 3075 EA
关键词
D O I
10.1007/BF01202225
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We investigated the potential of cross-over to the serotonin receptor (5HT3) antagonist ondansetron after protection failure with tropisetron. Several cases of complete protection were observed. These limited data suggest that there is an indication for retreatment with a different 5HT3 antagonist after an initial failure to another and also stress the need and relevance for comparative studies between 5HT3 antagonists.
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页码:126 / 127
页数:2
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