ACTIONS OF THYROTROPIN-RELEASING-HORMONE ON THE GASTRO-INTESTINAL FUNCTION IN MAN .2. INHIBITION OF PENTAGASTRIN-STIMULATED ACID SECRETION

被引:11
作者
DOLVA, LO
HANSSEN, KF
BERSTAD, A
机构
[1] Dept. of Medicine B, Aker Hospital, Oslo
关键词
Acid secretion; Pentagastrin; Thyrotropin-releasing hormone;
D O I
10.3109/00365527909179843
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The pentagastrin-stimulated gastric volume and acid output were measured with and without an i.v. thyrotropin-releasing hormone (TRH) infusion (666 μg/h). TRH inhibited the pentagastrin (6 μg/kg s.c.) stimulated volume to 67.5 ± 8.4% (p < 0.01) and the acid output to 65 ± 8.4% of control infusion values (mean ± S.E.M.). It is concluded that TRH inhibits the pentagastrin-stimulated gastric secretion in man. © 1979 Informa UK Ltd.
引用
收藏
页码:33 / 34
页数:2
相关论文
共 8 条
[1]  
BLOOM SR, 1978, GUT HORMONES
[2]  
DOLVA LO, 1978, SCAND J GASTROENT, V13, P599
[3]  
Hodges JL, 1964, BASIC CONCEPTS PROBA
[4]  
KONTUREK SJ, 1976, SCAND J GASTROENTERO, V11, P1
[5]  
LEPPALUTO J, 1978, ACTA PHYS SCAND
[6]   THYROTROPIN-RELEASING-HORMONE IN GASTROINTESTINAL-TRACT [J].
MORLEY, JE ;
GARVIN, TJ ;
PEKARY, AE ;
HERSHMAN, JM .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 79 (01) :314-318
[7]   SMALL DOSE OF SOMATOSTATIN INHIBITS PENTAGASTRIN STIMULATED GASTRIC-SECRETION OF ACID, PEPSIN AND INTRINSIC-FACTOR IN MAN [J].
SCHRUMPF, E ;
VATN, MH ;
HANSSEN, KF ;
MYREN, J .
CLINICAL ENDOCRINOLOGY, 1978, 8 (05) :391-395
[8]  
WAHREN J, 1976, LANCET, V2, P1213