CYTOLYTIC LYMPHOCYTE-T MEDIATED CHROMIUM-51 RELEASE VERSUS SPONTANEOUS RELEASE FROM BLAST AND SPLEEN-CELL TARGETS AT LOW-TEMPERATURES

被引：3

作者：

BALK, SP ^{[1
]}

MESCHER, MF ^{[1
]}

机构：

[1] HARVARD UNIV, SCH MED, DEPT PATHOL, BOSTON, MA 02115 USA

来源：

CELLULAR IMMUNOLOGY | 1981年 / 65卷 / 01期

关键词：

D O I：

10.1016/0008-8749(81)90065-4

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The rate of spontaneous 51Cr release from mouse spleen cell and lipopolysaccharide blast target cells is strongly temperature dependent. Between 32 and 37.degree. C the rate of spontaneous release increases dramatically with temperature. Cytolytic T lymphocyte-mediated lysis of these target cells is also temperature dependent but lysis does not increase greatly above 32.degree. C. The ratio of specific 51Cr release to spontaneous release can be significantly improved by doing 51Cr-release assays at temperatures < 37.degree. C.

引用

页码：201 / 205

页数：5

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