SERUM INHIBITION OF LYMPHOCYTE-TRANSFORMATION IN A CASE OF PULMONARY TUBERCULOSIS

被引：7

作者：

BARCLAY, GR ^{[1
]}

KELLER, AJ ^{[1
]}

VANSOMEREN, V ^{[1
]}

URBANIAK, SJ ^{[1
]}

机构：

[1] EASTERN GEN HOSP,DEPT MED,EDINBURGH,SCOTLAND

来源：

CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY | 1979年 / 14卷 / 04期

关键词：

D O I：

10.1016/0090-1229(79)90097-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Immunological function was investigated in a patient with pulmonary tuberculosis which was refractory to conventional chemotherapy. The patient failed to express delayed cutaneous hypersensitivity (DH) in vivo to antigens which stimulated her lymphocytes to proliferate in vitro. Her serum inhibited the in vitro proliferative responses of autologous lymphocytes, and of homologous lymphocytes from normal healthy individuals. This inhibitory activity was maximal during an acute febrile phase of her illness and diminished with eventual resolution of her tuberculosis. The relationship of this serum inhibitory activity to the immune response and possible implications for therapy are discussed. © 1979.

引用

页码：449 / 455

页数：7

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