EFFICACY OF PRILOCAINE-LIDOCAINE CREAM IN THE TREATMENT OF PREMATURE EJACULATION

Purpose: We evaluated the efficacy of a new lidocaine-prilocaine cream in prev Materials and Methods: An open pilot, unblinded study was done using lidocaine-prilocaine cream in II healthy, married men with-premature ejaculation without organic or erectile problems. The patients were instructed to apply 2.5 gm. of the cream 30 minutes before sexual contact and to cover the penis with a condom. Patients were asked to grade the effect of the cream on ejaculation after each application. Results: There was a significant improvement in premature ejaculation statistically and clinically. Five patients graded the result as excellent compared to baseline, 4 graded it as better and 2 claimed to have no change compared to ejaculation before use of the cream. No adverse effects were noted. Conclusions: These promising results should prompt a large double-blind placebo-controlled trial. If confirmed, this therapy may be a breakthrough in the treatment of the most common form of male sexual dysfunction.