ASYMMETRIC-SYNTHESIS OF 1-ARYL-1,2,3,4-TETRAHYDROISOQUINOLINES .1. ADDITION OF CHIRAL PHENYLACETALDEHYDE ACETALS TO ACYLIMINES

被引：14

作者：

WUNSCH, B

NERDINGER, S

机构：

[1] Institut für Pharmazie, Lebensmittelchemie der Universität München, D-80333 Munich

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 44期

关键词：

D O I：

10.1016/0040-4039(95)01716-U

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselectivity in the addition of the enantiomerically pure (2-bromophenyl)acetaldehyde acetals 3a-g to the acylimines 4a,b is investigated. Based on this reaction a novel asymmetric synthesis for the 1-phenyl-tetrahydroisoquinoline 8 is elaborated.

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页码：8003 / 8006

页数：4

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