CYCLIC NUCLEOTIDE LEVELS IN BRAINS OF CONTROL AND HYPERTENSIVE RATS

被引：9

作者：

VOLICER, L ^{[1
]}

ODONNELL, A ^{[1
]}

CHASE, A ^{[1
]}

GAVRAS, H ^{[1
]}

机构：

[1] BOSTON UNIV, SCH MED, INST CARDIOVASC, BOSTON, MA 02118 USA

来源：

LIFE SCIENCES | 1979年 / 24卷 / 02期

关键词：

D O I：

10.1016/0024-3205(79)90122-X

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Adenosine 3′, 5′-monophosphate (cyclic AMP) and guanosine 3′,5- monophosphate (cyclic GMP) levels were measured in seven brain areas of spontaneously hypertensive rats (SHR) and two groups of control rats. In cerebral cortex, hypothalamus, pons-medulla oblongata and cerebellum cyclic AMP levels were higher in SHR than in Wistar-Kyoto controls. Cyclic GMP levels were higher in SHR than in Wistar-Kyoto rats in all brain areas except for the striatum and hippocampus where the levels were lower. There were also some differences in cyclic nucleotide levels between Wistar-Kyoto and Wistar-Charles River controls. © 1979.

引用

页码：131 / 135

页数：5

共 36 条

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