ACTIVITY OF ENZYMES INVOLVED IN NOREPINEPHRINE BIOSYNTHESIS IN THE BROWN ADIPOSE-TISSUE OF THE DEVELOPING RAT - INFLUENCE OF HYPOTHYROIDISM

被引：3

作者：

BLOUQUIT, MF

GRIPOIS, D

机构：

[1] Laboratoire d'Endocrinologie, Universite Paris-Sud, F-91405 Orsay

来源：

HORMONE AND METABOLIC RESEARCH | 1990年 / 22卷 / 08期

关键词：

brown adipose tissue; developing rat; dopamine beta hydroxylase; hypothyroidism; tyrosine hydroxylase;

D O I：

10.1055/s-2007-1004938

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The activities of tyrosine hydroxylase (TH) and dopamine-beta-hydroxylase (DBH) were measured in vitro in the brown adipose tissue (BAT) of control and hypothyroid developing rats. Neonatal hypothyroidism slows the development of TH activity, as manifest in lower BAT TH activity, relative to controls, up to 20 days. This effect is more pronounced when the onset of hypothyroidism is induced prenatally. No clear effect of hypothyroidism on DBH activity was evident.

引用

页码：423 / 425

页数：3

共 13 条

[1]

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[2] TYROSINE CONTENT, INFLUX AND ACCUMULATION RATE, AND CATECHOLAMINE BIOSYNTHESIS MEASURED INVIVO, IN THE CENTRAL NERVOUS-SYSTEM AND IN PERIPHERAL ORGANS OF THE YOUNG-RAT - INFLUENCE OF NEONATAL-HYPOTHYROIDISM AND HYPERTHYROIDISM [J].