CLINICAL COURSE AFTER LIVER-TRANSPLANTATION IN PATIENTS WITH SARCOIDOSIS

被引：58

作者：

CASAVILLA, FA ^{[1
]}

GORDON, R ^{[1
]}

WRIGHT, HI ^{[1
]}

GAVALER, JS ^{[1
]}

STARZL, TE ^{[1
]}

VANTHIEL, DH ^{[1
]}

机构：

[1] UNIV PITTSBURGH, SCH MED, PITTSBURGH, PA 15261 USA

来源：

ANNALS OF INTERNAL MEDICINE | 1993年 / 118卷 / 11期

关键词：

LIVER TRANSPLANTATION; SARCOIDOSIS; CYCLOSPORINE; FK-506; LIVER DISEASES;

D O I：

10.7326/0003-4819-118-11-199306010-00007

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of liver transplantation and the obligate use of cyclosporine on the subsequent clinical course of nine patients with sarcoidosis were examined. Two comparison groups, each consisting of 18 patients without sarcoidosis, were also studied. The liver allograft recipients received either cyclosporine or FK 506 as their primary immunosuppressive agent. Patient and graft survival were assessed for all three groups. In patients with sarcoidosis before transplantation, evidence for continued disease activity after transplantation was also assessed. Patient and allograft survival were excellent. No clinical evidence of continued disease activity was noted. Thus, the presence of sarcoidosis is not a contraindication for liver transplantation in otherwise appropriate candidates for the procedure.

引用

页码：865 / 866

页数：2

共 11 条

[1]

BIELORY L, 1988, TRANSPLANT P, V20, P144

[2]

CUNNAH D, 1988, AM J MED, V85, P580

[3]

DUFFELL GM, 1992, MED PRACTICING PHYSI, P962

[4] ORAL CYCLOSPORINE IN THE TREATMENT OF INFLAMMATORY AND NONINFLAMMATORY DERMATOSES - A CLINICAL AND IMMUNOPATHOLOGIC ANALYSIS [J].