NMR AND X-RAY EVIDENCE THAT THE HIV PROTEASE CATALYTIC ASPARTYL GROUPS ARE PROTONATED IN THE COMPLEX FORMED BY THE PROTEASE AND A NONPEPTIDE CYCLIC UREA-BASED INHIBITOR

被引:126
作者
YAMAZAKI, T
NICHOLSON, LK
TORCHIA, DA
WINGFIELD, P
STAHL, SJ
KAUFMAN, JD
EYERMANN, CJ
HODGE, CN
LAM, PYS
RU, Y
JADHAV, PK
CHANG, CH
WEBER, PC
机构
[1] NIDR,BONE RES BRANCH,BETHESDA,MD 20892
[2] NIH,PROT EXPRESS LAB,BETHESDA,MD 20892
[3] DUPONT MERCK PHARMACEUT CO,DEPT CHEM & PHYS SCI,WILMINGTON,DE 19880
关键词
D O I
10.1021/ja00102a057
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[No abstract available]
引用
收藏
页码:10791 / 10792
页数:2
相关论文
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