MUTABILITY TOWARD ULTRAVIOLET LIGHT OF RECOMBINATION-DEFICIENT STRAINS OF ESCHERICHIA COLI

被引：166

作者：

WITKIN, EM

机构：

[1] State University of New York, Downstate Medical Center, Brooklyn, NY

来源：

MUTATION RESEARCH | 1969年 / 8卷 / 01期

关键词：

D O I：

10.1016/0027-5107(69)90135-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Strains having recA and recC mutations were tested for UV mutability. A recA strain is UV-stsable at doses that are demonstrably mutagenic in its Rec+ derivative. Strains of recC genotype are not UV-stable, but produce UV-induced mutations at frequencies significantly lower than those produced at the same doses in Rec+ strains. The results support the hypothesis that most UV-induced mutations originate as errors in recombinational repair of single-strand gaps in DNA. © 1966.

引用

页码：9 / &

共 18 条

[1]

BRIDGES BA, 1967, GENETICS, V57, P897

[2] BEGINNING OF A GENETIC ANALYSIS OF RECOMBINATION PROFICIENCY [J].