SYNTHESIS OF ISOTOPICALLY CHIRAL [C-13]PENCICLOVIR (BRL-39123) AND ITS USE TO DETERMINE THE ABSOLUTE-CONFIGURATION OF PENCICLOVIR TRIPHOSPHATE FORMED IN HERPES-VIRUS INFECTED-CELLS

被引：16

作者：

JARVEST, RL

BARNES, RD

EARNSHAW, DL

OTOOLE, KJ

SIME, JT

HODGE, RAV

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1990年 / 07期

关键词：

D O I：

10.1039/c39900000555

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：555 / 556

页数：2

共 9 条

[1] ANTIHERPESVIRUS ACTIVITY OF 9-(4-HYDROXY-3-HYDROXYMETHYLBUT-1-YL)GUANINE (BRL-39123) IN CELL-CULTURE [J].

BOYD, MR ;

BACON, TH ;

SUTTON, D ;

COLE, M .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1987, 31 (08) :1238-1242

[2] ANTIHERPESVIRUS ACTIVITY OF 9-(4-HYDROXY-3-HYDROXYMETHYLBUT-1-YL) GUANINE (BRL-39123) IN ANIMALS [J].

BOYD, MR ;

BACON, TH ;

SUTTON, D .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (03) :358-363

[3]

EARNSHAW DL, UNPUB

[4] SYNTHETIC STUDIES ON POLYETHER ANTIBIOTICS .5. TOTAL SYNTHESIS OF MONENSIN .2. STEREOCONTROLLED SYNTHESIS OF THE RIGHT HALF OF MONENSIN [J].

FUKUYAMA, T ;

WANG, CLJ ;

KISHI, Y .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (01) :260-262

[5] SYNTHESIS AND ANTIVIRAL ACTIVITY OF 9-[4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL]PURINES [J].

HARNDEN, MR ;

JARVEST, RL ;

BACON, TH ;

BOYD, MR .

JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (09) :1636-1642

[6]

HARNDEN MR, 1985, Patent No. 141927

[7] MODE OF ACTION OF 9-(4-HYDROXY-3-HYDROXYMETHYLBUT-1-YL)GUANINE (BRL 39123) AGAINST HERPES-SIMPLEX VIRUS IN MRC-5 CELLS [J].

HODGE, RAV ;

PERKINS, RM .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1989, 33 (02) :223-229

[8]

KANEKO T, 1960, CHEM IND-LONDON, P1187

[9] STEREOCHEMICAL CONSIDERATIONS IN THE ENZYMATIC PHOSPHORYLATION AND ANTIVIRAL ACTIVITY OF ACYCLONUCLEOSIDES .1. PHOSPHORYLATION OF 2'-NOR-2'-DEOXYGUANOSINE [J].

KARKAS, JD ;

GERMERSHAUSEN, J ;

TOLMAN, RL ;

MACCOSS, M ;

WAGNER, AF ;

LIOU, R ;

BOSTEDOR, R .

BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 911 (02) :127-135

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