THE PATHOGENESIS OF ATHEROMA AND THE RATIONALE FOR ITS TREATMENT

被引:11
作者
COLLINS, P [1 ]
FOX, K [1 ]
机构
[1] ROYAL BROMPTON NATL HEART & LUNG HOSP, LONDON SW3 6LY, ENGLAND
关键词
ATHEROMA; TREATMENT OF ATHEROMA; ENDOTHELIUM; PLATELETS;
D O I
10.1093/oxfordjournals.eurheartj.a060214
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Several theories have been proposed to explain the mechanism causing atheroma; these include endothelial cell injury, smooth muscle cell proliferation, lipid deposition and an abnormality of the vasa vasorum. Based on these hypotheses. new therapies aimed at causing regression or preventing the development of atheroma include heparin, calcium antagonists, beta-receptor antagonists, lipid lowering agents and drugs that manipulate platelets. © 1992 The European Society of Cardiology.
引用
收藏
页码:560 / 565
页数:6
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