BIOTRANSFORMATION OF SOME APHIDICOLANE DERIVATIVES BY CEPHALOSPORIUM-APHIDICOLA

被引：11

作者：

HANSON, JR ^{[1
]}

JARVIS, AG ^{[1
]}

RATCLIFFE, AH ^{[1
]}

机构：

[1] ICI PLC,MACCLESFIELD SK10 4TG,CHESHIRE,ENGLAND

来源：

PHYTOCHEMISTRY | 1992年 / 31卷 / 11期

关键词：

CEPHALOSPORIUM-APHIDICOLA; APHIDICOLIN; DITERPENOID BIOTRANSFORMATION;

D O I：

10.1016/S0031-9422(00)97540-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Chlorocholine chloride (CCC) is shown to inhibit the formation of aphidicolin by Cephalosporium aphidicola. 3alpha,18-Dihydroxyaphidicolane is transformed into aphidicolin, whereas 3alpha,16alpha,18-trihydroxyaphidicolane is converted into 16-epi-aphidicolin.

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收藏

页码：3851 / 3853

页数：3

相关论文

共 12 条

[1] STUDIES IN TERPENOID BIOSYNTHESIS .37. AN O-18 STUDY OF THE BIOSYNTHESIS OF THE DITERPENOID, APHIDICOLIN IN CEPHALOSPORIUM-APHIDICOLA [J].

ACKLAND, MJ ;

GORDON, J ;

HANSON, JR ;

YEOH, BL ;

RATCLIFFE, AH .

PHYTOCHEMISTRY, 1988, 27 (04) :1031-1033

[2] STUDIES IN TERPENOID BIOSYNTHESIS .35. BIOSYNTHETIC SEQUENCES LEADING TO THE DITERPENOID APHIDICOLIN IN CEPHALOSPORIUM-APHIDICOLA [J].

ACKLAND, MJ ;

GORDON, JF ;

HANSON, JR ;

YEOH, BL ;

RATCLIFFE, AH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1988, (06) :1477-1480

[3] STUDIES IN TERPENOID BIOSYNTHESIS .32. THE INCORPORATION OF APHIDICOL-16-ENE AND APHIDICOLAN-16-BETA-OL INTO THE DITERPENOID APHIDICOLIN BY THE FUNGUS CEPHALOSPORIUM-APHIDICOLA [J].

ACKLAND, MJ ;

HANSON, JR ;

YEOH, BL ;

RATCLIFFE, AH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1985, (12) :2705-2707

[4] STUDIES IN TERPENOID BIOSYNTHESIS .38. THE ROLE OF AN 16-BETA,17-EPOXYAPHIDICOLANE IN THE MINOR BIOSYNTHETIC-PATHWAY LEADING TO APHIDICOLIN [J].

ACKLAND, MJ ;

GORDON, JF ;

HANSON, JR ;

RATCLIFFE, AH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1988, (07) :2009-2012

[5] A UNIFIED MECHANISTIC VIEW OF OXIDATIVE REACTIONS CATALYZED BY P-450 AND RELATED FE-CONTAINING ENZYMES [J].

AKHTAR, M ;

WRIGHT, JN .

NATURAL PRODUCT REPORTS, 1991, 8 (06) :527-551

[6] EPOXIDATION OF UNSATURATED STEROIDS BY MICROORGANISMS [J].

BLOOM, BM ;

SHULL, GM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1955, 77 (21) :5767-5768

[7] PHYLLOCLADAN-16-BETA-OL (13-BETA-KAURAN-16-BETA-OL) [J].

CARMAN, RM .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1981, 34 (04) :923-926

[8] EFFECT OF PLANT GROWTH RETARDANTS ON BIOSYNTHESIS OF DITERPENES BY GIBBERELLA FUJIKUROI [J].

CROSS, BE ;

MYERS, PL .

PHYTOCHEMISTRY, 1969, 8 (01) :79-&

[9] STRUCTURE AND ABSOLUTE-CONFIGURATION OF ANTIBIOTIC APHIDICOLIN - TETRACYCLIC DITERPENOID CONTAINING A NEW RING-SYSTEM [J].

DALZIEL, W ;

HESP, B ;

STEVENSON, KM ;

JARVIS, JAJ .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1973, (23) :2841-2851

[10] THE MICROBIOLOGICAL TRANSFORMATION OF DITERPENOIDS [J].

HANSON, JR .

NATURAL PRODUCT REPORTS, 1992, 9 (02) :139-151