THE EFFECT OF A STIFF SPINAL IMPLANT AND ITS LOOSENING ON BONE-MINERAL CONTENT IN CANINES

被引：30

作者：

DALENBERG, DD ^{[1
]}

ASHER, MA ^{[1
]}

ROBINSON, RG ^{[1
]}

JAYARAMAN, G ^{[1
]}

机构：

[1] UNIV KANSAS,MED CTR,ORTHOPAED SURG SECT,39TH & RAINBOW BLVD,KANSAS CITY,KS 66103

来源：

SPINE | 1993年 / 18卷 / 13期

关键词：

STRESS SHIELDING; BONE MINERAL; SPINAL INSTRUMENTATION; LOOSENING;

D O I：

10.1097/00007632-199310000-00023

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A canine spine surgery model was used to study bone mineral loss induced in vertebrae bypassed by stiff implants. Loosening of implants was measured, and a determination was made as to the effect of loosening on the degree of bone mineral loss. Sixteen dogs were implanted with a rigid screw-rod construct and randomized to one of four groups depending on the motion segments immobilized. No fusions were performed. Bone mineral was studied by DEXA at baseline, and postoperatively at 3, 6, and 9 months. Loosening measurements were made at the implant-implant interface and the implant-bone interface at 9 months postoperatively. Results show that bone mineral loss occurred uniformly at 3 months postoperatively in vertebrae spanned by the implants, with the average bone mineral density at 3 months representing 81% of baseline. When the implant remained secure, bone mineral loss persisted at 6 and 9 months but did not worsen. When the implants loosened, there was recovery of bone mineral to the baseline level by 9 months postoperative.

引用

页码：1862 / 1866

页数：5

共 14 条

[1]

Engh C.A., Bobyn J.D., The influence of stem size and extent of porous coating on femoral bone resorption after primary cementless total hip arthroplasty, Clin Orthop, 231, pp. 7-28, (1988)

[2]

Farey I.D., McAfee P.C., Gurr K.R., Randolph M.A., Quantitative histologic study of the influence of spinal instrumentation on lumbar fusion: A canine model, J Orthop Res, 7, pp. 709-722, (1989)

[3]

Frost H.M., Symposium on the osteoporoses, Orthop Clin North Am, 12, pp. 725-726, (1981)

[4]

Goel V.K., Lim T.-H., Gwon J., Chen J.-Y., Winterbottom J.M., Park J.B., Weinstein J.N., Ahn J.-Y., Effects of rigidity of an internal fixation device: A comprehensive biomechanical investigation, Spine, 16, pp. 155-161, (1991)

[5]

Goel V.K., Lim T.-H., Gwon J., Winterbottom J.M., Park J.B., Weinstein J.N., Ahn J.-Y., Biomechanics of a stabilized motion segment as affected by the rigidity of a fixation device, (1992)

[6]

Gurr K.R., McAfee P.C., Warden K.E., Shih C.-M., Roentgen- ographic and biomechanical analysis of lumbar fusions, A Canine Model. J Orthop Res, 7, pp. 838-848, (1989)

[7]

Johnston C.E., Ashman R.B., Baird A.M., Allard R.N., Effect of spinal construct stiffness on early fusion mass incorporation: Experimental study, Spine, 15, pp. 908-912, (1990)

[8]

McAfee P.C., Farey I.D., Sutterlin C.E., Gurr K.R., Warden K.E., Cunningham B.W., The effect of spinal implant rigidity on vertebral bone density, A Canine Model. Spine, 16, pp. 90-97, (1991)

[9]

McAfee P.C., Farey I.D., Sutterlin C.E., Gurr K.R., Warden K.E., Cunningham B.W., Device-related osteoporosis with spinal instrumentation, Spine, 14, pp. 919-926, (1989)

[10]

Meade J.B., The adaptation of bone to mechanical stress: Experimentation and current concepts, Cowin SC, pp. 211-251, (1989)

← 1 2 →