ANISOTROPIC MOLECULAR-MOTION ON CELL-SURFACES

被引：89

作者：

SMITH, BA

CLARK, WR

MCCONNELL, HM

机构：

[1] STANFORD UNIV,STAUFFER LAB PHYS CHEM,STANFORD,CA 94305

[2] UNIV CALIF LOS ANGELES,DEPT BIOL,LOS ANGELES,CA 90024

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1979年 / 76卷 / 11期

关键词：

D O I：

10.1073/pnas.76.11.5641

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Photobleaching in a two-dimensional periodic pattern has been used to characterize the motion of succinylconcanavalin A receptors on the surfaces of mouse fibroblasts. These receptors were found to exhibit anisotropic two-dimensional diffusion in adherent cells having parallel stress fibers. Diffusion coefficients of the order of 10(-11) cm2/sec and 10(-12) cm2/sec were measured for diffusive motions parallel and perpendicular to these fibers. The determination of the anisotropic motion used a two-dimensional Fourier analysis. A study was made of the effect of changes in cell shape on the photobleach pattern.

引用

页码：5641 / 5644

页数：4

共 15 条

[1] ANTIBODY-INDUCED LINKAGES OF PLASMA-MEMBRANE PROTEINS TO INTRACELLULAR ACTOMYOSIN-CONTAINING FILAMENTS IN CULTURED FIBROBLASTS [J].